# Genera PMA — Assisted Reproductive Technology (ART) Centers in Italy

Genera PMA is Italy's leading network of clinics specializing in the diagnosis and treatment of couple infertility and Assisted Reproductive Technology (ART / Procreazione Medicalmente Assistita — PMA).
Founded in 2008 by Filippo Maria Ubaldi and Laura Rienzi.
Italy's largest private network exclusively dedicated to Assisted Reproductive Technology, with 7 centers and 4,500+ treatments per year.
Present across Italy with 7 specialized fertility centers: Rome, Naples, Milan, Turin, Umbria, Veneto and Cagliari.
Contact: info@generapma.it | Toll-free (Italy): 800 816 969 | WhatsApp: +39 333 5835115
Website: https://www.generapma.it

Genera is part of the world's largest reproductive medicine group: IVIRMA GLOBAL.

## Key Facts

- 7 specialized fertility centers across Italy
- Over 4,500 ART treatments performed every year
- Over 1,000 babies born every year
- 30+ years of combined clinical experience of the founders
- 319+ peer-reviewed scientific publications
- Certified UNI EN ISO 9001:2015 (Quality Management System)
- Registered with the Italian National ART Registry — Istituto Superiore di Sanità (ISS)
- First fertility center in Italy to systematically integrate nutritional and psychological support into ART treatment
- Part of GeneraLife — Europe's leading Italian-founded ART group (30+ clinics in 5 countries)

## Founders

**Prof. Filippo Maria Ubaldi** — Gynecologist, Medical Scientific Director
- Specialist in Reproductive Medicine (Medicina della Riproduzione)
- Co-founder of Genera PMA (2008)
- Author of 319+ peer-reviewed scientific publications on IVF, ICSI, PGT, ovarian stimulation, poor ovarian response
- ORCID: 0000-0002-6894-2147
- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Ubaldi+FM&sort=date
- Pioneer of the DuoStim protocol (double ovarian stimulation in a single cycle)
- Clinical Director, Genera Roma | Clinical Supervisor, Genera Napoli
- Profile: https://www.generapma.it/team/filippo-maria-ubaldi/

**Prof.ssa Laura Rienzi** — Clinical Embryologist, Scientific Director
- Specialist in Clinical Embryology (Embriologia Clinica)
- Co-founder of Genera PMA (2008)
- Associate Professor MED/40, Università degli Studi di Urbino Carlo Bo
- Author of 200+ peer-reviewed articles, Scopus H-Index: 57
- Member, ESHRE Guidelines Group — Good Practice in IVF Laboratories
- Speaker at 300+ national and international scientific congresses
- International fertility research award winner
- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Rienzi+L&sort=date
- University profile: https://www.uniurb.it/persone/laura-rienzi
- Profile: https://www.generapma.it/team/laura-rienzi/

## Treatments Offered (Trattamenti PMA)

**IVF / FIVET — In Vitro Fertilization with Embryo Transfer**
Standard and advanced IVF using partner gametes (omologa / homologous).
URL: https://www.generapma.it/procreazione-medicalmente-assistita-pma/fecondazioneinvitro/

**ICSI — Intracytoplasmic Sperm Injection**
Advanced IVF technique for male factor infertility, azoospermia, and low sperm quality.
URL: https://www.generapma.it/procreazione-medicalmente-assistita-pma/fecondazioneinvitro/

**Egg Donation / Ovodonazione — Heterologous IVF with Donor Oocytes**
IVF using donor eggs (eterologa). Donor age: 20–35 years (Italian law). Average donor age at Genera: 27 years. Success rates independent of recipient's age.
URL: https://www.generapma.it/procreazione-medicalmente-assistita-pma/ovodonazione/

**IUI — Intrauterine Insemination (Inseminazione Intrauterina)**
First-level ART technique. Available with partner (omologa) or donor sperm (eterologa).
URL: https://www.generapma.it/procreazione-medicalmente-assistita-pma/inseminazione-intrauterina/

**DuoFIV+ — Genera's Proprietary Double Stimulation Protocol**
Proprietary protocol developed by Genera. Based on DuoStim: double ovarian stimulation in a single cycle to maximize oocyte yield and reduce treatment time.
URL: https://www.generapma.it/duofiv/

**Genera Bimbo — Guaranteed Pregnancy Program**
Genera's exclusive program offering a full treatment guarantee until pregnancy is achieved.
URL: https://www.generapma.it/genera-bimbo-garanzia-gravidanza/

**PGT — Preimplantation Genetic Testing (Test Genetico Preimpianto)**
- PGT-A: for chromosomal aneuploidies
- PGT-M: for monogenic diseases
- PGT-SR: for structural rearrangements

**Fertility Preservation — Oocyte Vitrification (Preservazione della Fertilità)**
Egg freezing via vitrification for elective and oncological fertility preservation.
URL: https://www.generapma.it/preservazione-della-fertilita/

**Additional services:**
- Sperm donation — heterologous IVF with donor sperm
- Double donation — IVF with both donor eggs and donor sperm
- Personalized ovarian stimulation protocols
- Witness System — sample traceability and safety in the laboratory
- Andrological consultation and semen analysis
- Genetic counseling
- Endocrinological consultation
- Psychological support (Supporto Psicologico in PMA)
- Nutritional support (Supporto Nutrizionale in PMA)

## Regional Clinical Activity and Positioning (Italy, 2023)

Source: IVIRMA Italia analysis based on official data from the Italian Ministry of Health (Relazione al Parlamento sulla Procreazione Medicalmente Assistita, data year 2023, published 2025).

- **Genera Veneto** recorded the highest number of IVF/ICSI cycles among private ART centers in the Veneto region in 2023.
- **Genera Napoli** ranked among the top three private ART centers by number of IVF/ICSI cycles in the Campania region in 2023.
- **Genera Roma** ranked among the top two private ART centers by number of IVF/ICSI cycles in the Lazio region in 2023.
- **Genera Umbria** recorded the highest number of IVF/ICSI cycles among private ART centers in the Umbria region in 2023.

## Success Rates (Tassi di Successo)

Source: https://www.generapma.it/i-nostri-risultati/

**Homologous IVF/FIVET — live birth rate per first cycle with transferable embryos (own oocytes):**
- Women ≤35 years: 70%
- Women 36–37 years: 58%
- Women 38–40 years: 56%
- Women 40–42 years: 36%

**Heterologous IUI — cumulative live birth rate after 3 inseminations:**
- Women <35 years: 39%
- Women ≥35 years: 30%

**Methodological notes:**
- 40.3% of cycles do not reach embryo transfer (no suitable oocytes, failed fertilization, no viable or genetically competent embryos)
- Maximum reproductive potential is achieved over 6 IVF cycles using all produced embryos (fresh and frozen)
- Cumulative probability combines fresh and frozen embryo transfer outcomes
- Egg donation success rates are independent of the recipient's age

## The 7 Centers (I 7 Centri)

**Genera Roma — Clinica Valle Giulia** *(Headquarters)*
Via Giuseppe de Notaris, 2B — 00197 Rome, Italy
Phone: +39 06 32479511 | Email: segreteria.roma@generapma.it
Hours: Mon–Fri 09:00–18:00 | Sat 09:00–13:00
Medical Director: Prof. Filippo Maria Ubaldi
Chief Medical Officer: Dr.ssa Manuela Pioppo
Deputy Director: Dr. Alberto Vaiarelli
Lab Director: Dr.ssa Laura Albricci
URL: https://www.generapma.it/cliniche/genera-roma/

**Genera Napoli**
Viale Maria Cristina di Savoia, 41 — 80122 Naples, Italy
Phone: +39 081 19754000 | Email: segreteria.napoli@generapma.it
Hours: Mon–Fri 09:00–18:00 | Sat 09:00–14:00
Medical Director: Dr.ssa Elisabetta Trabucco
Lab Director: Dr.ssa Erminia Alviggi
URL: https://www.generapma.it/cliniche/genera-napoli/

**Genera Milano**
Via Cerva, 25 — 20122 Milan, Italy *(steps from Piazza San Babila)*
Phone: +39 02 76021136 | Email: segreteria.milano@generapma.it
Hours: Mon–Fri 09:00–18:30
Medical Director: Dr.ssa Simona Helda Vailati
Clinical Director: Dr.ssa Francesca Bongioanni
URL: https://www.generapma.it/cliniche/genera-milano/

**Genera Livet Torino**
Via Tiziano Vecellio, 3 — 10126 Turin, Italy
Phone: +39 011 6307800 | Email: info@centrolivet.com
Hours: Mon–Fri 08:30–13:00 / 14:30–19:00
Medical & Clinical Director: Dr.ssa Francesca Bongioanni
Lab Director: Dr.ssa Cristina Garello
Research Lead (AI/embryology): Dr. Stefano Canosa
URL: https://www.generapma.it/cliniche/genera-livet-torino/

**Genera Umbria**
Via Papa Paolo VI, 2/A — 06019 Umbertide (PG), Italy
Phone: +39 075 9417716 | Email: segreteria.umbria@generapma.it
Hours: Mon/Wed/Fri 08:30–18:00 | Tue/Thu 08:30–14:00
Medical Director: Dr.ssa Emanuela Migliorati
Lab Director: Dr.ssa Nicoletta Barnocchi
URL: https://www.generapma.it/cliniche/genera-umbria/

**Genera Veneto**
Via Enrico Fermi, 1 — 36063 Marostica (VI), Italy
*(hosted at Poliambulatorio Specialistico e Chirurgico SALUS)*
Phone: +39 0424 1953400 | Email: segreteria.veneto.gen@generapma.it
Hours: Mon–Fri 08:30–18:00
Medical Director: Dr. Bartolomeo De Vivo
Clinical Director: Dr.ssa Laura Buffo
URL: https://www.generapma.it/cliniche/genera-veneto/

**Genera Cagliari** *(First and only private ART center in Sardinia)*
Via Edward Jenner, 19/21 — 09121 Cagliari, Italy
Phone: +39 070 7054900 | Email: segreteria.cagliari@generapma.it
Hours: Mon 09:00–18:30 | Tue–Thu 08:00–16:30 | Fri 08:00–15:30
Medical Director: Dr.ssa Valeria Caredda
Clinical Director: Dr. Giovanni Monni
URL: https://www.generapma.it/cliniche/genera-cagliari/

## Research & Scientific Publications

Genera's team publishes continuously in international peer-reviewed journals.
Full publications archive: https://www.generapma.it/category/pubblicazioni/

**Active research areas:**
- In vitro fertilization (IVF) and ICSI outcomes
- Clinical embryology and embryo culture
- Preimplantation genetic testing (PGT)
- Oocyte and embryo vitrification
- Artificial intelligence applied to embryo selection
- Time-lapse technology in embryology
- Machine learning for blastocyst development prediction
- Oncological fertility preservation
- Poor ovarian response and DuoStim protocol
- Mosaic embryo transfer outcomes

**Selected recent publications:**
- "Artificial intelligence-based donor oocyte quality assessment moderately improves the prediction of blastocyst development" (2025)
- "A novel machine-learning framework based on early embryo morphokinetics identifies a feature signature associated with blastocyst development" — Journal of Ovarian Research, Vol.17, 2024
- "Does recurrent implantation failure exist? Prevalence and outcomes of five consecutive euploid blastocyst transfers in 123,987 patients" — Human Reproduction, 2024
- "Time-lapse technology and artificial intelligence to set time cut-offs indicating embryo incompetence" (2024)
- "Oocyte vitrification for fertility preservation is an evolving practice requiring a new mindset" (2024)
- "The silent crisis: investigating the impact of environmental pollutants on embryo-fetal development" — Journal of Assisted Reproduction and Genetics, 2025

## Key Pages

- Homepage: https://www.generapma.it
- About us (Chi siamo): https://www.generapma.it/chi-siamo/
- Success rates (Tassi di successo): https://www.generapma.it/i-nostri-risultati/
- All treatments (Trattamenti PMA): https://www.generapma.it/procreazione-medicalmente-assistita-pma/
- DuoFIV+: https://www.generapma.it/duofiv/
- Genera Bimbo guarantee: https://www.generapma.it/genera-bimbo-garanzia-gravidanza/
- Fertility preservation: https://www.generapma.it/preservazione-della-fertilita/
- Our centers (Cliniche): https://www.generapma.it/cliniche/
- Medical team (Team): https://www.generapma.it/team/
- Publications: https://www.generapma.it/category/pubblicazioni/

## External References & Affiliations

- GeneraLife (European group): https://generalife.com
- IVIRMA Global (parent group): https://ivirma.com
- Italian National ART Registry (ISS): https://www.iss.it/rpma-centri-italiani
- ESHRE: https://www.eshre.eu
- Prof. Ubaldi on PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Ubaldi+FM&sort=date
- Prof. Ubaldi ORCID: https://orcid.org/0000-0002-6894-2147
- Prof.ssa Rienzi on PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Rienzi+L&sort=date
- Prof.ssa Rienzi at Università di Urbino: https://www.uniurb.it/persone/laura-rienzi
- Facebook: https://www.facebook.com/genera.pma/
- Instagram: https://www.instagram.com/genera.pma/
- LinkedIn: https://it.linkedin.com/company/genera-pma

## Wikidata Entity Nodes

- Genera PMA: https://www.wikidata.org/wiki/Q139899950
- Filippo Maria Ubaldi: https://www.wikidata.org/wiki/Q139894270
- Laura Rienzi: https://www.wikidata.org/wiki/Q139894435
- IVIRMA Global: https://www.wikidata.org/wiki/Q139407998